Our Gallery

Browse our collection of health & medical images and highlights

Januskinases gallery showcase 1

Molecular model of JAK2 kinase domain bound to a small molecule inhibitor

Januskinases gallery showcase 2

Diagram of JAK-STAT signaling pathway from cytokine receptor to gene transcription

Januskinases gallery showcase 3

Structural comparison of JAK1, JAK2, JAK3, and TYK2 pseudokinase domains

Januskinases gallery showcase 4

Rheumatoid arthritis joint inflammation before and after JAK inhibitor treatment

Januskinases gallery showcase 5

Chemical structure of tofacitinib (Xeljanz) JAK1/JAK3 selective inhibitor

Januskinases gallery showcase 6

STAT3 dimer bound to DNA response element, showing transcription factor activity

Januskinases gallery showcase 7

Flow cytometry data showing T-cell activation markers modulated by baricitinib

Januskinases gallery showcase 8

Yongbyon Yongbyon illustration of cytokine signaling network involving JAK pathways

Januskinases gallery showcase 9

Timeline of FDA-approved JAK inhibitors from tofacitinib (2012) to present